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1

Gene therapy in Alzheimer’s disease – potential for disease modification

Per Nilsson, Nobuhisa Iwata, Shin-ichi Muramatsu, Lars O. Tjernberg, Bengt Winblad, Takaomi C. Saido

Journal:

Journal of Cellular and Molecular Medicine

Year:

2010

Language:

english

File:

PDF, 1.36 MB

english, 2010

2

Matrix-assisted laser desorption/ionization mass spectrometry of proteins extracted directly from sodium dodecyl sulphate-polyacrylamide gels

Hanno Ehring, Signhild Strömberg, Agneta Tjernberg, Bengt Norén

Journal:

Rapid Communications in Mass Spectrometry

Year:

1997

Language:

english

File:

PDF, 166 KB

english, 1997

3

Analysis of microdissected human neurons by a sensitive ELISA reveals a correlation between elevated intracellular concentrations of Aβ42 and Alzheimer’s disease neuropathology

Masakazu Hashimoto, Nenad Bogdanovic, Inga Volkmann, Mikio Aoki, Bengt Winblad, Lars O. Tjernberg

Journal:

Acta Neuropathologica

Year:

2010

Language:

english

File:

PDF, 1023 KB

english, 2010

4

Aβ43 is more frequent than Aβ40 in amyloid plaque cores from Alzheimer disease brains

Hedvig Welander, Jenny Frånberg, Caroline Graff, Erik Sundström, Bengt Winblad, Lars O. Tjernberg

Journal:

Journal of Neurochemistry

Year:

2009

Language:

english

File:

PDF, 757 KB

english, 2009

5

Collagenous Alzheimer amyloid plaque component assembles amyloid fibrils into protease resistant aggregates

Linda Söderberg, Camilla Dahlqvist, Hiroyoshi Kakuyama, Johan Thyberg, Akira Ito, Bengt Winblad, Jan Näslund, Lars O. Tjernberg

Journal:

Year:

2005

Language:

english

File:

PDF, 232 KB

english, 2005

6

Active γ-secretase is localized to detergent-resistant membranes in human brain

Ji-Yeun Hur, Hedvig Welander, Homira Behbahani, Mikio Aoki, Jenny Frånberg, Bengt Winblad, Susanne Frykman, Lars O. Tjernberg

Journal:

Year:

2008

Language:

english

File:

PDF, 880 KB

english, 2008

7

A novel approach for Aβ1–40 quantification using immuno-PCR

Masakazu Hashimoto, Mikio Aoki, Bengt Winblad, Lars O. Tjernberg

Journal:

Journal of Neuroscience Methods

Year:

2012

Language:

english

File:

PDF, 293 KB

english, 2012

8

Affinity pulldown of γ-secretase and associated proteins from human and rat brain

Yasuhiro Teranishi, Ji-Yeun Hur, Hedvig Welander, Jenny Frånberg, Mikio Aoki, Bengt Winblad, Susanne Frykman, Lars O. Tjernberg

Journal:

Journal of Cellular and Molecular Medicine

Year:

2010

Language:

english

File:

PDF, 1.49 MB

english, 2010

9

Erlin-2 is associated with active γ-secretase in brain and affects amyloid β-peptide production

Yasuhiro Teranishi, Ji-Yeun Hur, Gucci Jijuan Gu, Takahiro Kihara, Taizo Ishikawa, Takeshi Nishimura, Bengt Winblad, Homira Behbahani, Masood Kamali-Moghaddam, Susanne Frykman, Lars O. Tjernberg

Journal:

Biochemical and Biophysical Research Communications

Year:

2012

Language:

english

File:

PDF, 739 KB

english, 2012

10

CD147, a γ-secretase associated protein is upregulated in Alzheimer's disease brain and its cellular trafficking is affected by presenilin-2

Jarmila Nahalkova, Inga Volkmann, Mikio Aoki, Bengt Winblad, Nenad Bogdanovic, Lars O. Tjernberg, Homira Behbahani

Journal:

Neurochemistry International

Year:

2010

Language:

english

File:

PDF, 1.26 MB

english, 2010

11

P1-185 Analysis of single Alzheimer plaque cores by laser-capture microscopy and nano-electrospray/tandem mass spectrometry

Lars O. Tjernberg, Nenad Bogdanovic, Birgitta Axelsson, Bengt Winblad, Jan Näslund

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 163 KB

english, 2004

12

P1-233 Biochemical characterization of Alzheimer's related CLAC protein and binding to amyloid-β peptide

Linda Söderberg, Hiroyoshi Kakuyama, Bengt Winblad, Lars Tjernberg, Jan Näslund

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 159 KB

english, 2004

13

No association between polymorphisms in the neprilysin promoter region and Swedish Alzheimer's disease patients

Lena Lilius, Charlotte Forsell, Karin Axelman, Bengt Winblad, Caroline Graff, Lars Tjernberg

Journal:

Neuroscience Letters

Year:

2003

Language:

english

File:

PDF, 63 KB

english, 2003

14

A highly sensitive ELISA reveals intracellular accumulation of Aβ42 in microdissected human Purkinje neurons from Alzheimer brains

Lars O. Tjernberg, Masakazu Hashimoto, Nenad Bogdanovic, Inga Volkmann, Mikio Aoki, Bengt Winblad

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 64 KB

english, 2010

15

Gamma-secretase–associated proteins in detergent resistant membranes from brain

Ji-Yeun Hur, Yasuhiro Teranishi, Masakazu Hashimoto, Waltteri Hosia, Hedvig Welander, Bengt Winblad, Susanne Frykman, Lars O. Tjernberg

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 46 KB

english, 2010

16

The proximity ligation assay shows interaction between HCN2 and gamma-secretase

Mitsuhiro Inoue, Sophia Schedin Weiss, Birgitta Wiehager, Bengt Winblad, Susanne Frykman, Lars Tjernberg

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 62 KB

english, 2012

17

Monoamine oxidase B interacts with gamma-secretase: Confirmation with a new approach to the proximity ligation assay

Sophia Schedin Weiss, Susanne Frykman, Mitsuhiro Inoue, Yasuhiro Teranishi, Bengt Winblad, Lars Tjernberg

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 143 KB

english, 2012

18

The role of presenilin 1 familial Alzheimer's disease mutations for gamma-secretase activity and changed structural conformation

Patricia Lara Vasquez, Johanna Wanngren, Silvia Maioli, Lars Tjernberg, Bengt Winblad, Johan Lundkvist, IngMarie Nilsson, Helena Karlström

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 61 KB

english, 2012

19

Erlin-2 is associated with active gamma-secretase in brain

Yasuhiro Teranishi, Ji-Yeun Hur, Jijuan Gu, Homira Behbahani, Masood Kamali-Moghaddam, Bengt Winblad, Susanne Frykman, Lars Tjernberg

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 85 KB

english, 2012

20

Analysis of microdissected neurons by 18O mass spectrometry reveals altered protein expression in Alzheimer's disease

Masakazu Hashimoto, Nenad Bogdanovic, Hiroyuki Nakagawa, Inga Volkmann, Mikio Aoki, Bengt Winblad, Jun Sakai, Lars O. Tjernberg

Journal:

Journal of Cellular and Molecular Medicine

Year:

2012

Language:

english

File:

PDF, 723 KB

english, 2012

21

Synaptic and Endosomal Localization of Active γ-Secretase in Rat Brain

Frykman, Susanne, Hur, Ji-Yeun, Frånberg, Jenny, Aoki, Mikio, Winblad, Bengt, Nahalkova, Jarmila, Behbahani, Homira, Tjernberg, Lars O., Linden, Rafael

Journal:

Year:

2010

Language:

english

File:

PDF, 1.63 MB

english, 2010

22

Rat Brain γ-Secretase Activity Is Highly Influenced by Detergents †

Frånberg, Jenny, Welander, Hedvig, Aoki, Mikio, Winblad, Bengt, Tjernberg, Lars O., Frykman, Susanne

Journal:

Year:

2007

Language:

english

File:

PDF, 417 KB

english, 2007

23

Monoamine oxidase B is associated with γ-secretase in cultured neurons and in brain

Weiss, Sophia, Wiehager, Birgitta, Winblad, Bengt, Frykman, Susanne, Tjernberg, Lars

Journal:

Molecular Neurodegeneration

Year:

2013

Language:

english

File:

PDF, 66 KB

english, 2013

24

Activity-independent release of the amyloid β-peptide from rat brain nerve terminals

Lundgren, Jolanta L., Ahmed, Saheeb, Winblad, Bengt, Gouras, Gunnar K., Tjernberg, Lars O., Frykman, Susanne

Journal:

Neuroscience Letters

Year:

2014

Language:

english

File:

PDF, 940 KB

english, 2014

25

P3-328: Cleavage of endogenous substrates by γ-secretase in rat brain membranes

Frånberg, Jenny, Wiehager, Birgitta, Winblad, Bengt, Karlström, Helena, Tjernberg, Lars O., Frykman, Susanne

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 58 KB

english, 2008

26

P1-451: The oligomerization of amyloid-β peptide

Stone, Lisa A., Frykman, Susanne, Winblad, Bengt, Tjernberg, Lars O.

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 54 KB

english, 2008

27

In-solution analysis of beta-amyloid

Wennmalm, Stefan, Bark, Niklas, Winblad, Bengt, Widengren, Jerker, Tjernberg, Lars

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 55 KB

english, 2012

28

Prizes for rehabilitation and occupational medicine

Welander, Hedvig, Winblad, Bengt, Tjernberg, Lars O.

Journal:

Year:

1992

Language:

english

File:

PDF, 167 KB

english, 1992

29

P1-469: Long amyloid-β peptide variants in Alzheimer's disease brains

Welander, Hedvig, Winblad, Bengt, Tjernberg, Lars O.

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 56 KB

english, 2008

30

P4-201: Inhibitor pulldown of γ-secretase and associated components from human and rat brain

Teranishi, Yasuhiro, Welander, Hedvig, Frånberg, Jenny, Hur, Ji-Yeun, Aoki, Mikio, Nakagawa, Hiroyuki, Sakai, Jun, Winblad, Bengt, Tjernberg, Lars

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 57 KB

english, 2008

31

P4-200: Active γ-secretase is enriched in synaptic membranes prepared from rat brain

Frykman, Susanne, Nahalkova, Jarmila, Hur, Ji-Yeun, Frånberg, Jenny, Behbahani, Homira, Winblad, Bengt, Tjernberg, Lars

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 56 KB

english, 2008

32

Screening method of Amyloid β oligomerization inhibitors using a novel FRET probe

Ishikawa, Taizo, Bark, Niklas, Kakuyama, Hiroyoshi, Nishimura, Takeshi, Winblad, Bengt, Tjernberg, Lars

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 54 KB

english, 2011

33

Radiation therapy of ovarian carcinoma: Presentation of a six-field technique

Einhorn, Nina, von Hamos, Karin, Hindmarsh, Tomas, Lagergren, Curt, Lundell, Marie, Mellstedt, Hkan, Tjernberg, Bengt

Journal:

Radiotherapy and Oncology

Year:

1986

Language:

english

File:

PDF, 1.61 MB

english, 1986

34

Affinity purification of gamma-secretase associated proteins in synaptic membranes and synaptic vesicles

Frykman, Susanne, Kihara, Takahiro, Yamamoto, Natsuko Goto, Teranishi, Yasuhiro, Winblad, Bengt, Tjernberg, Lars O.

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 46 KB

english, 2010

35

P3-414

Frånberg, Jenny, Welander, Hedvig, Winblad, Bengt, Tjernberg, Lars O., Frykman, Susanne

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 68 KB

english, 2006

36

P4-202: Active γ-secretase is localized to detergent resistant membranes in human brain

Hur, Ji-Yeun, Welander, Hedvig, Behbahani, Homira, Aoki, Mikio, Frånberg, Jenny, Winblad, Bengt, Frykman, Susanne, Tjernberg, Lars O.

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 57 KB

english, 2008

37

P4-258 Localization of nicastrin/presenilin/APH-1/PEN-2 complexes to mitochondria

Hansson, Camilla A., Frykman, Susanne, Farmery, Mark R., Tjernberg, Lars O., Nilsberth, Camilla, Winblad, Bengt, Cowburn, Richard F., Thyberg, Johan, Ankarcrona, Maria

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 170 KB

english, 2004

38

Affinity pulldown of gamma-secretase and associated proteins from human and rat brain

Teranishi, Yasuhiro, Hur, Ji-Yeun, Welander, Hedvig, Frånberg, Jenny, Aoki, Mikio, Winblad, Bengt, Frykman, Susanne, Tjernberg, Lars O.

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 46 KB

english, 2010

39

P1-480: Amyloid β-peptide levels in laser capture microdissected CA1 pyramidal neurons of Alzheimer's brain

Aoki, Mikio, Volkmann, Inga, Tjernberg, Lars, Winblad, Bengt, Bogdanovic, Nenad

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 58 KB

english, 2008

40

The role of protein glycosylation in Alzheimer disease

Schedin-Weiss, Sophia, Winblad, Bengt, Tjernberg, Lars O.

Journal:

Year:

2014

Language:

english

File:

PDF, 399 KB

english, 2014

41

Folding into a β-Hairpin Can Prevent Amyloid Fibril Formation †

Hosia, Waltteri, Bark, Niklas, Liepinsh, Edvards, Tjernberg, Agneta, Persson, Bengt, Hallén, Dan, Thyberg, Johan, Johansson, Jan, Tjernberg, Lars

Journal:

Year:

2004

Language:

english

File:

PDF, 193 KB

english, 2004

42

Analysis of Single Alzheimer Solid Plaque Cores by Laser Capture Microscopy and Nanoelectrospray/Tandem Mass Spectrometry

Söderberg, Linda, Bogdanovic, Nenad, Axelsson, Birgitta, Winblad, Bengt, Näslund, Jan, Tjernberg, Lars O.

Journal:

Year:

2006

Language:

english

File:

PDF, 520 KB

english, 2006

43

Human brain proteins showing neuron-specific interactions with γ-secretase

Inoue, Mitsuhiro, Hur, Ji-Yeun, Kihara, Takahiro, Teranishi, Yasuhiro, Yamamoto, Natsuko G., Ishikawa, Taizo, Wiehager, Birgitta, Winblad, Bengt, Tjernberg, Lars O., Schedin-Weiss, Sophia

Journal:

Year:

2015

Language:

english

File:

PDF, 801 KB

english, 2015

44

Stress Conditions Increase Vimentin Cleavage by Omi/HtrA2 Protease in Human Primary Neurons and Differentiated Neuroblastoma Cells

Lucotte, Bérangère, Tajhizi, Mehdi, Alkhatib, Dareen, Samuelsson, Eva-Britt, Wiehager, Birgitta, Schedin-Weiss, Sophia, Sundström, Erik, Winblad, Bengt, Tjernberg, Lars.O, Behbahani, Homira

Journal:

Molecular Neurobiology

Year:

2015

Language:

english

File:

PDF, 4.79 MB

english, 2015

45

Adam10 and bace1 are localized to synaptic vesicles

Winblad, Bengt, Lundgren, Jolanta, Ahmed, Saheeb, Schedin-Weiss, Sophia, Gouras, Gunnar K., Tjernberg, Lars O., Frykman, Susanne

Journal:

Alzheimer's & Dementia

Year:

2015

Language:

english

File:

PDF, 70 KB

english, 2015

46

Roentgenographic and toxicologic studies on lead edta

Tjernberg, Bengt

Journal:

Acta Radiologica (Old Series)

Year:

1957

Language:

english

File:

PDF, 541 KB

english, 1957

47

A GLYCOMICS APPROACH FOR ANALYZING CEREBROSPINAL FLUID

Gaunitz, Stefan, Schedin-Weiss, Sophia, Winblad, Bengt, Tjernberg, Lars

Journal:

Alzheimer's & Dementia

Year:

2014

Language:

english

File:

PDF, 167 KB

english, 2014

48

REGULATION OF APP PROCESSING BY POTASSIUM/SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED ION CHANNEL 2

Frykman, Susanne, Inoue, Mitsuhiro, Ikeda, Atsushi, Teranishi, Yasuhiro, Kihara, Takahiro, Yamamoto, Natsuko Goto, Winblad, Bengt, Weiss, Sophia Schedin, Tjernberg, Lars

Journal:

Alzheimer's & Dementia

Year:

2014

Language:

english

File:

PDF, 57 KB

english, 2014

49

NEURON-SELECTIVE GAMMA-SECRETASE INTERACTIONS WITH PROTEINS EXPRESSED IN HUMAN BRAIN

Weiss, Sophia Schedin, Inoue, Mitsuhiro, Yamamoto, Natsuko Goto, Ishikawa, Taizo, Wiehager, Birgitta, Winblad, Bengt, Tjernberg, Lars O.

Journal:

Alzheimer's & Dementia

Year:

2014

Language:

english

File:

PDF, 56 KB

english, 2014

50

DISTINCT LOCALIZATION OF BETA- AND GAMMA-SECRETASE IN RAT BRAIN SYNAPSES

Lundgren, Jolanta Linnea, Ahmed, Saheeb, Weiss, Sophia Schedin, Winblad, Bengt, Gouras, Gunnar K., Tjernberg, Lars O., Frykman, Susanne

Journal:

Alzheimer's & Dementia

Year:

2014

Language:

english

File:

PDF, 215 KB

english, 2014